Does this meta-analysis indicate that smm does not necessarily lead to a mm diagnosis?

"the cumulative probability of progression was 73% at 15 years."

In addition, do any smmers believe that therapies (conventional, cam, etc.) improve these odds?

"Conclusions The risk of progression from smoldering multiple myeloma to symptomatic disease is related to the proportion of bone marrow plasma cells and the serum monoclonal protein level at diagnosis."

http://content.nejm.org/c...